Multiple Choice Questions: Antianginal Drugs
Which of the following antianginal drugs primarily works by releasing nitric oxide?
a) Metoprolol
b) Nitroglycerin
c) Amlodipine
d) Ranolazine
Beta-blockers used in angina treatment primarily:
a) Increase coronary blood flow
b) Reduce myocardial oxygen demand
c) Cause vasodilation of peripheral arteries
d) Increase cardiac contractility
Which calcium channel blocker is known for its significant effect on heart rate and AV node conduction?
a) Nifedipine
b) Amlodipine
c) Verapamil
d) Felodipine
Ranolazine's mechanism of action involves:
a) Blocking calcium channels
b) Inhibiting the late sodium current
c) Releasing nitric oxide
d) Blocking beta-adrenergic receptors
Which antianginal drug can cause visual disturbances as a side effect?
a) Isosorbide mononitrate
b) Metoprolol
c) Ivabradine
d) Diltiazem
Trimetazidine is classified as:
a) A nitrate
b) A beta-blocker
c) A calcium channel blocker
d) A metabolic modulator
Which of the following is NOT a common side effect of nitrates?
a) Headache
b) Hypotension
c) Hyperglycemia
d) Flushing
The primary mechanism of action for ivabradine is:
a) Inhibition of the If current in the sinoatrial node
b) Blockade of calcium channels
c) Vasodilation of coronary arteries
d) Reduction of cardiac contractility
Which antianginal drug is most likely to cause bronchospasm in susceptible patients?
a) Amlodipine
b) Isosorbide dinitrate
c) Propranolol
d) Ranolazine
The phenomenon of tolerance is most commonly associated with which class of antianginal drugs?
a) Beta-blockers
b) Calcium channel blockers
c) Nitrates
d) Metabolic modulators
Which antianginal drug works by shifting cardiac metabolism from fatty acid to glucose oxidation?
a) Nitroglycerin
b) Verapamil
c) Atenolol
d) Trimetazidine
The primary effect of calcium channel blockers in angina treatment is:
a) Increasing heart rate
b) Vasodilation
c) Enhancing cardiac contractility
d) Inhibiting platelet aggregation
Which of the following is true about ranolazine?
a) It is used as first-line therapy for acute angina attacks
b) It significantly reduces blood pressure
c) It is primarily used as add-on therapy for chronic angina
d) It has a strong negative inotropic effect
The risk of orthostatic hypotension is highest with which class of antianginal drugs?
a) Beta-blockers
b) Nitrates
c) Calcium channel blockers
d) Metabolic modulators
Which antianginal drug is contraindicated in patients taking phosphodiesterase-5 inhibitors.