2023年5月26日星期五

JNC 8 The Latest Hypertension Guidelines


JNC 8: The Latest Hypertension Guidelines


The Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC) is a panel of experts who provide evidence-based guidelines for the diagnosis, treatment, and prevention of hypertension. The JNC has released eight sets of guidelines since 1977, with the most recent being JNC 8, which was released in 2014. In this article, we will discuss the latest hypertension guidelines outlined in JNC 8.


JNC 8 provides updated recommendations for the diagnosis, treatment, and prevention of hypertension. The guidelines define hypertension as a systolic blood pressure of 140 mm Hg or higher or a diastolic blood pressure of 90 mm Hg or higher. The guidelines recommend that blood pressure be measured in both arms at the initial visit and that an average of two or more readings be taken at subsequent visits.


For the treatment of hypertension, JNC 8 recommends a target blood pressure of less than 140/90 mm Hg for most adults. For adults aged 60 years or older, a target blood pressure of less than 150/90 mm Hg is recommended. The guidelines recommend lifestyle modifications, such as weight loss, physical activity, and a healthy diet, as the first-line treatment for hypertension. If lifestyle modifications are not effective, medication may be prescribed.


JNC 8 also provides specific recommendations for the choice of medication based on age, race, and comorbidities. For example, for non-black patients with hypertension, thiazide diuretics, ACE inhibitors, angiotensin receptor blockers (ARBs), or calcium channel blockers (CCBs) may be used as first-line therapy. For black patients with hypertension, thiazide diuretics or CCBs are recommended as first-line therapy.


The guidelines recommend that medication dosages be adjusted based on the patient's response to treatment and that multiple medications be used if necessary to achieve the target blood pressure. The guidelines also emphasize the importance of medication adherence and follow-up visits to monitor blood pressure and adjust treatment as needed.


In addition to the diagnosis and treatment of hypertension, JNC 8 also provides recommendations for the prevention of hypertension. The guidelines recommend lifestyle modifications, such as weight loss, physical activity, and a healthy diet, as the primary means of preventing hypertension. The guidelines also recommend that adults with prehypertension (systolic blood pressure of 120-139 mm Hg or diastolic blood pressure of 80-89 mm Hg) be advised to make lifestyle modifications and that medication be considered for those at high risk of cardiovascular disease.


In conclusion, JNC 8 provides updated recommendations for the diagnosis, treatment, and prevention of hypertension. The guidelines emphasize the importance of lifestyle modifications as the first-line treatment for hypertension and provide specific recommendations for medication based on age, race, and comorbidities. By following the JNC 8 guidelines, healthcare providers can provide evidence-based care for patients with hypertension and improve patient outcomes. 

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