Antianginal Drugs_ An Overview

Antianginal Drugs: An Overview

Slide 1: Introduction

Definition of angina pectoris

Importance of antianginal drugs in management

Slide 2: Goals of Antianginal Therapy

Reduce frequency and severity of anginal attacks

Improve exercise tolerance

Enhance quality of life

Prevent complications

Slide 3: Major Classes of Antianginal Drugs

Nitrates

Beta-blockers

Calcium channel blockers

Newer agents (Ranolazine, Ivabradine)

Slide 4: Nitrates

Mechanism: NO donors, vasodilation

Examples: Nitroglycerin, Isosorbide mononitrate

Uses: Acute relief, prophylaxis

Side effects: Headache, hypotension

Key point: Tolerance development

Slide 5: Beta-blockers

Mechanism: Block beta-adrenergic receptors

Examples: Metoprolol, Atenolol, Propranolol

Uses: Chronic stable angina, post-MI

Side effects: Bradycardia, fatigue

Key point: First-line therapy for many patients

Slide 6: Calcium Channel Blockers

Mechanism: Block calcium influx into cells

Types: Dihydropyridines vs.