Classification of Antianginal Drugs_ SlideShare Presentation

Classification of Antianginal Drugs: SlideShare Presentation

Slide 1: Title

”Classification of Antianginal Drugs”

Slide 2: Introduction

Definition of angina pectoris

Importance of antianginal drugs in managing coronary artery disease

Slide 3: Overview of Classification

Organic Nitrates

Beta-Blockers

Calcium Channel Blockers

Potassium Channel Activators

Late Sodium Current Inhibitors

If Channel Inhibitors

Metabolic Modulators

Slide 4: Organic Nitrates

Mechanism: Vasodilation via nitric oxide release

Examples: Nitroglycerin, Isosorbide mononitrate, Isosorbide dinitrate

Key points: Rapid onset, risk of tolerance, various formulations

Slide 5: Beta-Blockers

Mechanism: Decrease heart rate and myocardial contractility

Examples: Metoprolol, Atenolol, Propranolol

Key points: Effective for acute and chronic angina, caution in asthma/COPD

Slide 6: Calcium Channel Blockers

Mechanism: Vasodilation and reduced myocardial oxygen demand

Examples: Amlodipine, Diltiazem, Verapamil

Key points: Dihydropyridines vs. non-dihydropyridines, effects on heart rate

Slide 7: Potassium Channel Activators

Mechanism: Vasodilation through K+ channel activation

Example: Nicorandil (not available in all countries)

Key points: Dual mechanism (K+ channel opener and nitrate-like effects)

Slide 8: Late Sodium Current Inhibitors

Mechanism: Reduces intracellular calcium overload

Example: Ranolazine

Key points: Add-on therapy, minimal hemodynamic effects

Slide 9: If Channel Inhibitors

Mechanism: Selective heart rate reduction

Example: Ivabradine

Key points: Alternative to beta-blockers, visual side effects

Slide 10: Metabolic Modulators

Mechanism: Optimize cardiac energy metabolism

Example: Trimetazidine (not available in all countries)

Key points: Add-on therapy, well-tolerated

Slide 11: Combination Therapy

Rationale for combining drug classes

Common combinations and their benefits

Slide 12: Considerations in Drug Selection

Patient factors (age, comorbidities)

Type and severity of angina

Potential drug interactions

Side effect profiles

Slide 13: Future Directions

Emerging therapies and research areas

Personalized medicine approaches

Slide 14: Conclusion

Summary of main drug classes

Importance of individualized treatment plans

Slide 15: References

List of key references and guidelines

This SlideShare presentation provides a comprehensive overview of antianginal drug classification, highlighting key mechanisms, examples, and important considerations for each class. The visual format allows for easy comparison between drug classes and emphasizes critical points for clinical decision-making.