Here's an overview of some important antianginal drugs, categorized by their primary mechanisms of action:
Organic Nitrates:
Nitroglycerin (Glyceryl trinitrate)
Isosorbide dinitrate
Isosorbide mononitrate
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Beta-Blockers:
Propranolol
Metoprolol
Atenolol
Bisoprolol
Carvedilol
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Calcium Channel Blockers:
a) Dihydropyridines:
Nifedipine
Amlodipine
Felodipine
b) Non-dihydropyridines:
Verapamil
Diltiazem
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Potassium Channel Openers:
Nicorandil
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Late Sodium Current Inhibitor:
Ranolazine
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If Channel Inhibitor:
Ivabradine
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Metabolic Modulators:
Trimetazidine
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Vasodilators:
Dipyridamole
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Antiplatelet Agents (often used in combination):
Aspirin
Clopidogrel
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Angiotensin-Converting Enzyme (ACE) Inhibitors:
Ramipril
Enalapril
Lisinopril
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Angiotensin Receptor Blockers (ARBs):
Losartan
Valsartan
Telmisartan
These drugs work through various mechanisms to improve blood flow to the heart, reduce cardiac workload, or modify metabolic processes to alleviate angina symptoms. The choice of medication depends on the patient's specific condition, comorbidities, and individual response to treatment. Often, a combination of these drugs is used for optimal management of angina pectoris.
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