Sedatives: A Comprehensive List of Medications
Sedatives are a class of medications designed to induce relaxation, reduce anxiety, and promote sleep. They work by depressing the central nervous system, slowing down brain activity. Here's a comprehensive list of sedative medications, categorized by their drug classes:
Benzodiazepines:
Alprazolam (Xanax)
Diazepam (Valium)
Lorazepam (Ativan)
Clonazepam (Klonopin)
Temazepam (Restoril)
Triazolam (Halcion)
Oxazepam (Serax)
Chlordiazepoxide (Librium)
Z-drugs (Non-benzodiazepine hypnotics):
Zolpidem (Ambien)
Zaleplon (Sonata)
Eszopiclone (Lunesta)
Barbiturates:
Phenobarbital
Secobarbital (Seconal)
Pentobarbital (Nembutal)
Amobarbital (Amytal)
Antihistamines with sedative properties:
Diphenhydramine (Benadryl)
Doxylamine (found in some OTC sleep aids)
Hydroxyzine (Vistaril, Atarax)
Antidepressants with sedative effects:
Trazodone
Mirtazapine (Remeron)
Amitriptyline
Doxepin
Antipsychotics with sedative properties:
Quetiapine (Seroquel)
Olanzapine (Zyprexa)
Risperidone (Risperdal)
Opioids (with sedative side effects):
Morphine
Codeine
Oxycodone
Other sedatives:
Melatonin (hormone supplement)
Ramelteon (Rozerem)
Suvorexant (Belsomra)
Gabapentin (Neurontin) - used off-label for sleep
Pregabalin (Lyrica) - used off-label for sleep
Anesthetic agents (used in medical settings):
Propofol
Ketamine
Etomidate
Herbal sedatives (not FDA-regulated):
Valerian root
Chamomile
Passionflower
Lavender
It's crucial to note that many of these medications, especially benzodiazepines, barbiturates, and opioids, carry significant risks of dependence and side effects. They should only be used under medical supervision. The choice of sedative depends on the specific condition being treated, the patient's overall health, potential drug interactions, and the risk of side effects. Always consult with a healthcare professional before using any sedative medication.
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